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The Metroid Prime Theme is, as the name implies, the main theme of Metroid Prime. It is also featured in the Opening/Menu (Metroid Prime) song in Super Smash Bros. Brawl. The track includes crackling and squeaking noises, possibly relating to Phazon. While being its own song, it incorporates the iconic notes from the Title theme. On the Metroid Prime & Fusion Original Soundtracks, this theme is simply called Title. Aside from the Title Screen, it also plays in the Concept Gallery for the game.
The theme is present in Metroid Prime 2: Echoes Bonus Disc, where it is used in The Metroid Chronicle while playing a movie with clips of Prime. Metroid Prime Trilogy also features the theme as one song that can be purchased in the Soundtrack Gallery. Part of the theme plays on the Title Screen and Samus Data Screen of Metroid Fusion.
A remix of the Metroid Prime Theme is used as the title theme of Metroid Prime Hunters: First Hunt. This version uses lower-quality instruments due to the limits of the Nintendo DS hardware. The result sounds "grittier" and more tense than the original theme.
The Metroid Prime Theme was used in the First Look trailer for Metroid Prime 4, which was showcased during the Nintendo Spotlight on June 13, 2017.
The Prime theme can be heard here: [1] The First Hunt theme can be heard here: [2]